https://www.paindetectives.org/about-us daily 1.0 2024-09-26 https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/1517800103817-ZOPFYNKHJQMX3D1WERL7/Airplane.jpg Home https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/1556661367327-7XYLV84WH6ZH6LL44IGL/image-asset.jpeg Home https://www.paindetectives.org/our-impact-mojave daily 0.75 2025-05-12 https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/1511895374951-T706SRX8FIBM47UBTF1J/Misty+sunrise.jpg Our Impact https://images.squarespace-cdn.com/content/v1/56e049e08a65e26059119cd5/1459879174445-MIOY5PULB1XAW864NVA8/img-06.jpg Our Impact https://www.paindetectives.org/introduction daily 0.75 2017-10-24 https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/1508869177058-HD8FL49ZDI37YHXVPOF0/Freudenberg_sg_Switzerland.jpg Introduction https://www.paindetectives.org/intro daily 0.75 2017-10-24 https://images.squarespace-cdn.com/content/v1/5310cef7e4b08602cbfa36bf/1395951531371-UHVVQPY7DU2MY6Z73FW2/hayden-header.jpg Intro https://images.squarespace-cdn.com/content/v1/5310cef7e4b08602cbfa36bf/1412380936909-3NDYSVN9D7FZDQHHCO0P/image-asset.jpeg Intro https://images.squarespace-cdn.com/content/v1/5310cef7e4b08602cbfa36bf/1412380988400-7DYABALOM24UK4TSXH5L/image-asset.jpeg Intro https://images.squarespace-cdn.com/content/v1/5310cef7e4b08602cbfa36bf/1412381139286-DM6BAWCRHNKPBLGZ3QER/Lima01.jpg Intro https://www.paindetectives.org/home daily 0.75 2017-10-24 https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/1508874388387-0ES9NWOI87JQAAC0UIVE/Freudenberg_sg_Switzerland.jpg OPTIMIZING THE MANAGEMENT OF PAIN AND IRRITABILITY IN CHILDREN WITH SEVERE NEUROLOGICAL IMPAIRMENT https://images.squarespace-cdn.com/content/v1/56cb3cba59827e93fe59b7ff/1456937093367-KZFXOYMZOMSAJU9MPSEO/image-asset.jpeg OPTIMIZING THE MANAGEMENT OF PAIN AND IRRITABILITY IN CHILDREN WITH SEVERE NEUROLOGICAL IMPAIRMENT https://images.squarespace-cdn.com/content/v1/56cb3cba59827e93fe59b7ff/1456937109909-T0NRUBU5L1NZWH0G78CA/image-asset.jpeg OPTIMIZING THE MANAGEMENT OF PAIN AND IRRITABILITY IN CHILDREN WITH SEVERE NEUROLOGICAL IMPAIRMENT https://images.squarespace-cdn.com/content/v1/56cb3cba59827e93fe59b7ff/1456937126692-IN2XXNF0H65F023MWZIE/image-asset.jpeg OPTIMIZING THE MANAGEMENT OF PAIN AND IRRITABILITY IN CHILDREN WITH SEVERE NEUROLOGICAL IMPAIRMENT https://www.paindetectives.org/testimonials daily 0.75 2016-03-02 https://images.squarespace-cdn.com/content/v1/56cb3cba59827e93fe59b7ff/1456938953605-64M27TNZ3BKT4PTE7VE2/header-testimonials-JessieWebster_Treehouse_20.jpg Past Projects and Publications https://images.squarespace-cdn.com/content/v1/56cb3cba59827e93fe59b7ff/1456860801571-YRX56NCYQBA7X6F56RVM/image-asset.png Past Projects and Publications https://images.squarespace-cdn.com/content/v1/56cb3cba59827e93fe59b7ff/1456860814473-EFM4C03QYY29DX49N3X8/image-asset.png Past Projects and Publications https://images.squarespace-cdn.com/content/v1/56cb3cba59827e93fe59b7ff/1456860866781-KQRKUA5211IJ8UQ32Z8G/image-asset.png Past Projects and Publications https://images.squarespace-cdn.com/content/v1/56cb3cba59827e93fe59b7ff/1456860882885-VEAFMYL7ZKEMVNFFNPY5/image-asset.png Past Projects and Publications https://www.paindetectives.org/the-country-annex daily 0.75 2018-02-28 https://images.squarespace-cdn.com/content/v1/56cb3cba59827e93fe59b7ff/1458686673103-AZIBMVIE3RRIK3KNPO0V/header-country-annex-JessieWebster_Squarespace_09.jpg Recruitment https://www.paindetectives.org/the-attic-loft daily 0.75 2017-10-24 https://images.squarespace-cdn.com/content/v1/56cb3cba59827e93fe59b7ff/1458685925146-28SMIJZTBO0BDCAIU98N/header-attic-loft-JessieWebster_Lifestyle_36.jpg About Our Study https://www.paindetectives.org/the-woodhouse daily 0.75 2017-10-24 https://images.squarespace-cdn.com/content/v1/56cb3cba59827e93fe59b7ff/1456938925579-VT88IS3K4LTE5BX3367D/header-woodhouse-JessieWebster_Treehouse_22.jpg Team Members https://www.paindetectives.org/contact-us daily 0.75 2025-10-27 https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/7daf075a-2b24-48fe-97ed-b9ff70a609e0/070525_vsantos_BCCH_Batch2_Extras_13.jpg Contact Us https://www.paindetectives.org/pilot-study daily 0.75 2024-02-14 https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/1562185849794-QD0IX7ADMIB9U76X1Y57/image001.jpg Pilot Study https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/1516988997006-45VV5NX194UVVDE1IFV7/Pill_Bottle_Spilled.jpg Pilot Study https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/1516315059206-OP3H2UASB0Z2W6KZ0SEX/Book_sale_loot_%284552277923%29.jpg Pilot Study https://www.paindetectives.org/results daily 0.75 2017-12-04 https://www.paindetectives.org/patient-oriented-research daily 0.75 2025-10-30 https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/c89e9e3b-4b63-4816-9c3e-5b8bb864b988/070525_vsantos_BCCH_Batch2_Family2_43.jpg Patient Oriented Research https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/5e2c098e-73cf-473e-ad38-e38ba6dec183/070525_vsantos_BCCH_Batch2_Family2_05.jpg Patient Oriented Research https://www.paindetectives.org/pain-we-cant-explain daily 0.75 2025-10-27 https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/1562185640378-ZALSACS02N59EL3WSH9W/image002.jpg Pain we Can't Explain - What is pain? https://www.paindetectives.org/our-team daily 0.75 2026-01-08 https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/408a3b27-26fd-4364-a1b8-80d74b7100c3/070525_vsantos_BCCH_Portraits_Group_02.jpg Our Team - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/fcb15895-673a-4e60-b5d2-efb5e1de4b20/070525_vsantos_BCCH_Portraits_01.jpg Our Team - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.paindetectives.org/about-piuo daily 0.75 2018-02-28 https://www.paindetectives.org/publications-and-infographics daily 0.75 2026-01-08 https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/0f712523-4586-44d0-8863-3500e2836676/Screenshot+2026-01-06+at+11.27.51%E2%80%AFAM.png Publications and Infographics - Make it stand out Insights From the International Consensus on Neuro-Irritability in Pediatric Palliative Care by Anna Mercante, Harold Siden, Justin Nathaniel Baker, Danai Papadatou, Huda Abu-Saad Huijer, Boris Zernikow, Julie Hauer, and Franca Benini, for the Neuro-Irritability and Pediatric Palliative Care Group https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/8d7a8c82-45bf-481d-b28a-a4b2dee53c85/Screenshot+2024-10-09+at+11.31.19%E2%80%AFAM.jpg Publications and Infographics - Make it stand out Exploring what motivates parents of children with medical complexity to participate in research by Laesa Kim, Anne-Mette Hermansen, Karen Cook and Harold Siden https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/1728497628491-YA8A22LTBM5YJA2WBWA6/Screenshot%2B2024-10-09%2Bat%2B11.07.33%25E2%2580%25AFAM.jpg Publications and Infographics - Make it stand out "Pain Management for Children with a Developmental Disability in a Primary Care Setting" by Harold Siden and Tim Oberlander in Pain in Children: A Practical Guide for Primary Care https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/1c19fb32-96e4-40a5-921c-a6fbf958f5cd/Screenshot+2024-10-09+at+11.18.40%E2%80%AFAM.jpg Publications and Infographics Evaluation of children with severe neurological impairment admitted to hospital with pain and irritability by Isobel Fishman, Harold Siden and Christina Vadeboncoeur https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/fe3f221e-f111-43ca-8c1f-ad2da5a86d95/Screenshot+2026-01-08+at+12.24.27%E2%80%AFPM.png Publications and Infographics - Make it stand out The Parental Experience of Caring for a Child with Pain and Irritability of Unknown Origin by Sara Rizakos, Arpita Parmar, Harold Siden, and Julia Orkin https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/84e11eee-d5ff-4cb2-97dd-b9b2e154fec1/Screenshot+2024-10-09+at+11.15.56%E2%80%AFAM.jpg Publications and Infographics - Make it stand out Physician variability in treating pain and irritability of unknown origin in children with severe neurological impairment by Harold Siden, Bruce Carleton, and Tim Oberlander https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/1a4afc12-b13c-4106-9563-6107e1720dfb/Screenshot+2026-01-06+at+11.40.52%E2%80%AFAM.png Publications and Infographics - Make it stand out Partnering with families to manage pain and irritability in children with severe neurological impairments: the creation and evaluation of the parent monitoring board by Laesa Kim https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/8ba714ee-fb62-41fe-9464-ceae782514b0/Screenshot+2024-10-09+at+12.48.08%E2%80%AFPM.jpg Publications and Infographics - Make it stand out Bringing the pain and irritability of unknown origin (PIUO) pathway to community pediatric practices in BC: development of an implementation strategy by Sharon Hou https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/502cf111-3020-4326-93a2-54d8b098066d/Screenshot+2026-01-06+at+11.41.16%E2%80%AFAM.png Publications and Infographics - Make it stand out Barriers and facilitators to implementing a clinical pathway in community practice: insights from community pediatricians in British Columbia by Candice Barrans https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/58aaf0e2-f51c-4ba2-85f2-dc3a47e5693d/Screenshot+2024-10-09+at+12.47.12%E2%80%AFPM.jpg Publications and Infographics - Make it stand out Implementing the pain and irritability of unknown origin (PIUO) pathway in community pediatric practices: an an integrated knowledge mobilization plan by Hanna Huguet https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/68153d77-b810-46cc-8a65-bed25a1da660/Screenshot+2026-01-06+at+11.41.39%E2%80%AFAM.png Publications and Infographics - Make it stand out Implementing the pain pathway in community pediatric practice: development of an implementation plan by Gabriel Zamma https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/f52afb72-a9cf-474c-ab65-c7cec4fef84a/Screenshot+2024-10-09+at+12.46.39%E2%80%AFPM.jpg Publications and Infographics - Make it stand out Integrating knowledge mobilization in the pain and irritability of unknown origin implementation study by Hanna Huguet https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/93c59f47-7802-4f70-8c84-bea2898210c8/Screenshot+2024-10-09+at+11.35.44%E2%80%AFAM.jpg Publications and Infographics - Make it stand out A standardized approach to idiopathic pain in children with neurological conditions by Harold Siden, Tim Oberlander, Ashley Wilson and Shalu Duggal https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/7d92dd48-9f04-4082-8bf0-42ff1f13323c/Screenshot+2024-10-09+at+11.36.06%E2%80%AFAM.jpg Publications and Infographics - Make it stand out The PIUO Study: Optimizing the Management of Pain and Irritability of Unkown Origin in Children with Severe Neurological Impairment by Harold Siden and Anne-Mette Hermansen https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/45831acf-ff72-4b80-91fd-02e2f4549e5d/Screenshot+2024-10-09+at+11.36.26%E2%80%AFAM.jpg Publications and Infographics - Make it stand out Exploring What Motivates Parents of Children Living with Medical Complexity to Participate in Research Studies: An Interpretive Descriptive Study by Laesa Kim and Karen Cook https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/05ef6057-4a1e-43c4-828c-3f4f3b55db8c/Screenshot+2024-10-09+at+12.27.30%E2%80%AFPM.jpg Publications and Infographics - Make it stand out Pain Detectives: Optimizing the Management of Pain and Irritability of Unknown Origin in Children with Severe Neurological Impairment by Katie Ketchum https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/576540f0-941d-4414-a28e-d3a3987c7739/Screenshot+2024-10-09+at+12.29.10%E2%80%AFPM.jpg Publications and Infographics - Make it stand out Exploring Parental Stress Associated with Caring for Children with Unexplained Pain: A Qualitative Sub-Study by Sarah Rikazos https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/ee5b6085-eaf3-4646-b3e5-b84ff942e3e8/Screenshot+2024-10-09+at+12.29.47%E2%80%AFPM.jpg Publications and Infographics - Make it stand out Caregiver-reported nociceptive pain responses in children with significant neurological impairment by Emily Johnston https://www.paindetectives.org/posters daily 0.75 2020-08-04 https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/1596517740959-0JKMX5EKKGT5BHWRB5ZA/Pain+Detectives+PIOU+by+Katie+Ketchum.jpg Posters https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/1594671472206-LPZGIBZ0MNNABNEVCZHD/Sara+Rizakos+PIUO+Poster+.jpg Posters https://www.paindetectives.org/new-page daily 0.75 2024-02-13 https://www.paindetectives.org/gabapentin-trial daily 0.75 2024-09-26 https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/b7aba686-8e31-480d-94b4-6496e6470a98/image-asset.jpg Gabapentin Trial This study is accepting participants. If you would like to learn about enrollment click here or contact research Coordinator Anne-Mette Hermansen at 604 875 2000 ext. 6909 or ahermansen@bcchr.ca https://www.paindetectives.org/piuo-study-1 daily 0.75 2025-10-30 https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/a126d411-ed76-42a2-97e5-1c261a99ccbf/070525_vsantos_BCCH_Batch2_Family2_07.jpg PIUO Phase I PIUO Phase I ran from 2017-2022. 72 kids enrolled across four sites in Vancouver, Calgary, Ottawa and Toronto. We followed the participants over months, investigating their unexplained pain and providing pain management support. Analysis of the data collected during the study is now underway. https://www.paindetectives.org/piuo-phase-ii daily 0.75 2025-10-28 https://www.paindetectives.org/terms-of-service-mojave daily 0.75 2025-05-12 https://www.paindetectives.org/privacy-policy-mojave daily 0.75 2025-05-12 https://www.paindetectives.org/impact-join-mojave daily 0.75 2025-05-12 https://images.squarespace-cdn.com/content/v1/56e049e08a65e26059119cd5/1459870151243-UM5MND5R89JE6VXSI8T1/img-07.jpg Join https://www.paindetectives.org/get-involved daily 0.75 2025-10-27 https://www.paindetectives.org/presentations-media daily 0.75 2026-01-07 https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/26e54962-f477-4f80-912f-68cc4a7ffaef/Screenshot+2026-01-06+at+11.12.08%E2%80%AFAM.png Presentations & Media https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/cbe11dcc-fff7-46ef-99c6-fe4683850cf3/Child+Healthcare+Canada_November+2025.webp Presentations & Media https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/572cce56-c3cf-4327-b421-3776a57b0b6d/HOU+%2B+KIM_Child-Bright+Webinar_Implementation+Science+%281080+x+1080+px%29.jpg Presentations & Media - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/7e7f1997-c334-46fe-a2db-8582ff64d614/Screenshot+2025-10-07+at+11.54.27%E2%80%AFAM.png Presentations & Media https://www.paindetectives.org/our-study-team daily 0.75 2026-01-14 https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/fcb15895-673a-4e60-b5d2-efb5e1de4b20/070525_vsantos_BCCH_Portraits_01.jpg Our Study Team - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/a07b594a-bcc9-407e-a4d8-66281a24da61/stephanie+glegg.jpg Our Study Team - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/8d053c29-75a1-42bd-be17-7af9f06dc3c1/Tim+Oberlander+photo+2024.jpg Our Study Team - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/6f28c9be-288d-4150-81e3-73792b2397ce/caroline+sanders.png Our Study Team - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/85ba4060-5a72-4e65-a31a-24b1fe549f24/Sharon+Hou.jpg Our Study Team - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/71f22858-8e58-4f0a-9768-f339aeb80094/Gail+Andrews.jpg Our Study Team - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/d7d5c91a-3144-4e90-9fc1-b445452e93f0/Laesa+Kim.jpg Our Study Team - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/f7b557ed-58f4-48cb-8c25-a70361cace2a/Anne-Mette+Hermansen.jpg Our Study Team - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.paindetectives.org/implementation-infographic daily 0.75 2025-10-18 https://images.squarespace-cdn.com/content/v1/59ef7d4d32601e21e28939b3/e2b810aa-45ea-4875-9d24-99450927be1e/CIHR+Infographic+-+HOU+and+HUGUET.png Implementation Infographic - Make it stand out Whatever it is, the way you tell your story online can make all the difference.